Effects of noninvasive ventilation combined with bronchoalveolar lavage in patients with AECOPD with respiratory failure
10.3760/cma.j.issn.1008-6706.2016.22.015
- VernacularTitle:无创通气联合支气管镜肺泡灌洗治疗慢性阻塞性肺疾病急性发作伴呼吸衰竭的效果观察
- Author:
Yu LIU
- Publication Type:Journal Article
- Keywords:
Pulmonary disease,chronic obstructive;
Respiratory failure;
Noninvasive ventilation;
Bronchoscopy
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(22):3419-3422
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application effects of noninvasive ventilation combined with bron-choalveolar lavage in patients with AECOPD with respiratory failure.Methods 70 patients with AECOPD and respir-atory failure were chosen,and they were divided into control group and observation group,both two groups were treated with routine treatment,the control group combined with noninvasive ventilation,the observation group combined with bronchoalveolar lavage on the basis of the control group.Blood gas index,intubation rate,hospital stay and time of invasive ventilation between the two group were compared.Results After treatment,PaO2 and PaCO2 in the control group were (61.20 ±11.23)mmHg,(56.27 ±15.42)mmHg,which in the observation group were (73.04 ± 8.58)mmHg,(47.25 ±11.18)mmHg.PaO2 and PaCO2 of the two groups were improved compared with before treat-ment,which of the observation group were better than the control group,the differences were statistically significant (t =4.956,2.802,all P <0.05).Intubation rate of the observation group was 5.71%,which was 22.85% in the control group,the difference between the two groups was statistically significant(χ2 =4.200,P <0.05).Total intuba-tion rate had no significant difference between the two groups(P >0.05).Invasive ventilation time,hospital stay in the control group were (8.19 ±3.92)d,(10.43 ±4.11)d,which were higher than (6.21 ±1.43)d,(8.30 ±1.68)d in the observation group,the differences were statistically significant(t =2.807,2.838,all P <0.05 ).Conclusion Noninvasive ventilation combined with bronchoalveolar lavage could effectively improve the serum index and early intubation rate,and with short invasive ventilation time and hospital stay,it is worth promoting.
