A Case of Anaphylactic Reactions to Isosulfan Blue Dye in A Cervical Cancer Patient.
- Author:
Chae Chun RHIM
1
;
Sung Eun NAMKOONG
Author Information
1. Department of Obstetrics and Gynecology, Catholic University Medical College, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Anaphylactic reactions;
Isosulfan blue dye;
Sentinel lymph node
- MeSH:
Anaphylaxis*;
Biopsy;
Breast Neoplasms;
Cervix Uteri;
Colloids;
Drainage;
Female;
Humans;
Lymph Nodes;
Melanoma;
Neoplasm Metastasis;
Uterine Cervical Neoplasms*;
Vulvar Neoplasms
- From:Korean Journal of Obstetrics and Gynecology
2003;46(2):484-487
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The sentinel lymph node is defined as the first node of a regional lymphatic basin that receives the lymphatic drainage from a tumor, thus representing an elective site of lymph node metastasis. According to the sentinel lymph node hypothesis, histologically negative sentinel lymph nodes can guarantee the histological negativity of the remaining regional lymph nodes. These assumptions suggest that the sentinel node can be a suitable marker of regional lymph node status. Thus sentinel node biopsy may be a reasonable alternative to unnecessary pelvic lymph nodes dissection and a suitable method for limited control of early stage cervical cancer. To improve the sentinel node detection in surgical procedures, we investigated lymphatic mapping of sentinel lymph nodes with isosulfan blue dye (lymphazur 1%) and technetium-99m colloid albumin. We have made it a rule to inject 5 ml of isosulfan blue dye in the peritumoral area of cervix. It is reported that isosulfan blue dye has been safe and easily used in the detection of sentinel lymph node in melanoma, breast cancer and vulvar cancer. We experienced a case of anaphylactic reactions to isosulfan blue dye in cervical cancer patient, so we report it with a brief review of literature.
