Research advances on epigenetic mechanisms of depression
10.16571/j.cnki.1008-8199.2016.10.019
- VernacularTitle:抑郁症的表观遗传学机制研究进展
- Author:
Ning XU
;
Guangfen ZHANG
;
Haiying YU
;
Zhiqiang ZHOU
- Publication Type:Journal Article
- Keywords:
Depression;
Epigenetics;
DNAmethylation;
Histonemodification;
miRNA
- From:
Journal of Medical Postgraduates
2016;29(10):1093-1096
- CountryChina
- Language:Chinese
-
Abstract:
Depression is a common mental disease, which mainly presents with a state of low mood and aversion to activity. Epigenetics is to study the influence of structural modification of pre?transcriptional gene to gene function in chromatin level. Recent studies have found that epigenetic mechanisms including DNA methylation, histone modification, and non?coding RNA regulation play important roles in the pathogenesis of depression. This article reviews the research advances on epigenetic mechanisms of depression.
