The effect of notch signaling in chondrocytes differentiation
10.16571/j.cnki.1008-8199.2016.10.023
- VernacularTitle:Notch信号通路在软骨细胞分化过程中的作用
- Author:
Gang LIU
;
Lei ZHANG
;
Shijie FU
- Publication Type:Journal Article
- Keywords:
Notch signaling;
Mesenchymal progenitor cell;
Cartilage cells;
Cartilage
- From:
Journal of Medical Postgraduates
2016;29(10):1111-1115
- CountryChina
- Language:Chinese
-
Abstract:
Notch signaling is an important evolutionarily conserved pathway involving the fate of cells translation. Additional?ly, this pathway also plays an important role in cartilage formation and maintenance of chondrocytes phenotype, regulation of the prolif?eration, maturation and balance of cartilage matrix metabolism. This paper reviews the composition and activation process of notch sig?naling, and its specific role in cartilage formation.