The efficacy of itraconazole and miconazole nitrate for recurrent monilial vaginitis
10.3760/cma.j.issn.1008-6706.2016.21.016
- VernacularTitle:伊曲康唑联合硝酸咪康唑治疗复发性假丝酵母菌阴道炎疗效观察
- Author:
Xumin XIE
;
Suping LAN
;
Miaomiao XIE
- Publication Type:Journal Article
- Keywords:
Cardidiasis vulvovaginal;
Itraconazole;
Miconazole nitrate
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(21):3263-3266
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the treatment effect of joint nitric acid imidazole and itraconazole on recurrent candida vaginitis.Methods 200 confirmed cases of patients with recurrent candida vaginitis in our hospital during October 2014 to June 2015 were selected and divided into research group and the control group with random indicator method,with 100 cases in each group.The control group were treated by nitric acid imidazole vaginal soft capsule,with vaginal drug delivery,which shoud put suppository in vaginal depths after washing,for one times a night and one soft capsule every time,and a week was a period of treatment.The patients in the research group received basis treatment of the control group adding itraconazole capsules(200mg per day,oral).8 weeks after treatment,the patients in this process were reviewed to analyzed clinical efficacy and adverse reactions occured.Results The total effective rate of the research group was 98%,which of the control group was 73%,the difference was statistically significant(χ2 =25.21,P <0.01).The incidence of adverse of patients in the research group was 13%,which of the control group was 14%,there was no statistically significant difference (χ2 =0.04,P >0.05 ).Conclusion The curative effect of itraconazole joint miconazole nitratet to recurrent monilial vaginitis is superior to the use of miconazole nitrate alone, with less adverse reaction,and is easy to use.It is worth clinical application.