Research progression of AMPK in adjuvant treatment strategy of breast cancer
10.16571/j.cnki.1008-8199.2016.09.022
- VernacularTitle:腺苷酸活化的蛋白激酶在乳腺癌辅助治疗中作用的研究进展
- Author:
Tao CHEN
;
Huijuan ZENG
;
Shaohua WANG
- Publication Type:Journal Article
- Keywords:
Breast cancer;
AMPK signaling pathway;
Energy metabolism
- From:
Journal of Medical Postgraduates
2016;29(9):993-998
- CountryChina
- Language:Chinese
-
Abstract:
Activated protein kinase ( AMPK) , an important energy receptor , plays a very important role in regulating organ-ism and the energy metabolism of the cell .AMPK has complex relationship with survival of different types of breast cancer cells .Ac-cording to different conditions , AMPK may exist both anti or promoting effect on tumor .In this review , we summarize the relationship between AMPK and breast cancer related signal pathways , AMP and breast cancer endocrine therapy , breast cancer chemotherapy , ra-diotherapy for breast cancer , treatment of triple negative breast cancer and multi drug resistance of the relationship , we also expound some drugs related to AMPK and used in clinical setting .
