Progress in functions of microRNA-494 and related mechanism
10.3969/j.issn.1000-4718.2016.10.029
- VernacularTitle:MicroR NA-494参与多种疾病发生发展的分子机制研究进展
- Author:
Guangwen LI
;
Haiping ZHAO
;
Yumin LUO
- Publication Type:Journal Article
- Keywords:
MicroRNA-494;
Tumor;
Ischemia;
Hypoxia
- From:
Chinese Journal of Pathophysiology
2016;32(10):1909-1915
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA-494 (miR-494) is one of the microRNAs from 14q32.31 miR-gene cluster.Recently, miR-494 was found to closely relate with tumors and other diseases .This article reviews the expression changes , roles and possible regulatory mechanisms of miR-494 in multiple tumors and other hypoxia/ischemia diseases .Recent studies demon-strate that the expression of miR-494 is affected by many factors , and miR-494 could be a biomarker of diagnosis , staging and prognosis in tumors and other diseases , and a target of therapy in future .
