Effect of Intravesical Botulinum Toxin Injection on Pain of Bladder Pain Syndrome:A Meta-analysis
10.3969/j.issn.1006-9771.2016.10.024
- VernacularTitle:膀胱内注射肉毒毒素对膀胱疼痛综合征疼痛程度影响的Meta分析
- Author:
Jie ZHANG
;
Qiang WANG
;
Zengchun WANG
;
Zigang REN
;
Wei XIONG
;
Haiquan LIU
;
Junjie WANG
;
Tingting FAN
- Publication Type:Journal Article
- Keywords:
bladder pain syndrome;
Botulinum toxin;
intravesical injection;
randomized controlled trials;
Meta analysis
- From:
Chinese Journal of Rehabilitation Theory and Practice
2016;22(10):1222-1226
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systemically evaluate the effect of intravesical Botulinum toxin on pain of patientspain syndrom. Methods The following databases as Cochrane Library, PubMed, Web of Science, Embase, Springer, Wiley, Science Direct, OVID were searched to col-lect the randomized controlled trials (RCTs) with the treatment of intravesical Botulinum toxin vs. 0.9%sodium chloride for patients with bladder pain syndrome. Two reviewers screened the trials according to the inclusion and exclusion criterias, extracted the data, assessed the quality, and the changes of Visual Analogue Scales (VAS) before and after treatment were used to conduct Meta analysis with RevMan5.2 software. Results Five studies were included with a total of 218 patients, there were 127 cases in intravesical Botulinum toxin group and 91 cases in 0.9%sodium chloride group. Meta analysis showed that the pain relief effect of intravesical Botulinum toxin was better than that of 0.9%sodium chloride. Conclusion Intravesical Botulinum toxin can relieve the pain of patients with bladder pain syndrome.
