Preliminary Evaluation of Coronary Artery Disease by Dual-source CT Functional Imaging in Relevant Patients
10.3969/j.issn.1000-3614.2016.09.002
- VernacularTitle:冠状动脉双源计算机断层摄影术血管功能成像评价冠心病的初步研究
- Author:
Qingfeng XIONG
;
Xiaojing MA
;
Yan CHEN
;
Xin CHEN
;
Wei LI
;
Dongsi SHUANG
;
Juan XU
;
Lin LI
;
Xianfeng CHEN
- Publication Type:Journal Article
- Keywords:
Coronary artery disease;
Tomography,X-ray computed;
Coronary angiography;
Flow reserve
- From:
Chinese Circulation Journal
2016;31(9):836-839
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To preliminarily evaluate coronary heart disease (CAD) by dual-source CT vascular functional imaging in relevant patients. Methods: A total of 200 patients with suspected non-ST elevation acute coronary syndrome (NSTE-ACS) in our hospital from 2014-09 to 2015-10 were enrolled, 57 of them received dual-source CT angiography (DSCTA) and diagnosed for critical value of left anterior descending (LAD) stenosis; the patients were further examined by selective coronary angiography (SCA) within 1 week to conifrm the degree of stenosis. Meanwhile, fractional lfow reserve (FFR) was measured and taking FFR 0.8 as cut off point, the patients were divided into 2 groups: FFR<0.8 group,n=27 and FFR≥0.8 group,n=30. The values of left ventricular anterior wall, side wall, left ventricular cavity and the segmental thickness in diastolic and systolic stages were measured; relative CT value between ventricular anterior wall and side wall was compared, myocardium thickness at the end-diastolic stage was also compared. Results:①In FFR<0.8 group, compared with the side wall, anterior wall had decreased relative CT value (P=0.000), myocardium thickness at the end-diastolic stage (P=0.000) and myocardial wall thickening rate (P=0.001).②In FFR≥0.8 group, compared with the side wall, anterior wall had decreased relative CT value (P=0.000), myocardium thickness at the end-diastolic stage (P=0.018), while similar myocardial wall thickening rate (P=0.186).③Compared with FFR≥0.8 group, the patients in FFR<0.8group presented reduced relative CT value in anterior wall (P<0.05) and myocardial wall thickening rate (P<0.001), while similar myocardium thickness at the end-diastolic stage (P=0.964). Conclusion: CT information may provide the reference value for treating patients in clinical practice.
