Effect of Danshen injections on NT-proBNP in patients with hypertension and left ventricular failure
10.3969/j.issn.1673-4130.2016.19.027
- VernacularTitle:丹参注射液对高血压合并左心室心力衰竭患者B型脑钠肽的影响
- Author:
Jibao QIN
;
Ling JIANG
- Publication Type:Journal Article
- Keywords:
Danshen injection;
hypertension;
heart failure;
NT-proBNP
- From:
International Journal of Laboratory Medicine
2016;37(19):2728-2729
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Danshen injection on brain peptide type B (NT‐proBNP) in patients with hyperten‐sion and left ventricular failure ,provide an effective basis for clinical treatment .Methods Totally 80 patients of hypertension with left heart failure from February 2015 to February 2016 were randomly divided into two groups :40 patients were treated with con‐ventional therapy (control group ) ,40 patients in the conventional treatment combined with Danshen injection (experimental group) .We compared NT‐proBNP ,inflammatory factors and clinical efficacy between two groups .Results Before treatment ,the expression of NT‐proBNP and hs‐CRP ,NT‐proBNP level was basically the same in two groups (P> 0 .05) .After treatment ,the ex‐perimental group of patients with NT‐proBNP was significantly lower than the control group and the LVEF ,left ventricular mass index and left ventricular volume index were significantly higher compared with the control group (P< 0 .05) .The total effective rate of patients in Danshen injection groups was significantly higher (P< 0 .05) .Conclusion The injection of Danshen in patients with hypertension and heart failure patients can significantly improving NT‐proBNP levels and improve the cardiac function .
