Correlation Analysis of Subclinical Hypothyroidism With its Treatment in Patients After Coronary Artery Bypass Grafting
10.3969/j.issn.1000-3614.2016.09.010
- VernacularTitle:亚临床甲状腺功能减退与冠状动脉旁路移植术后患者院内治疗相关性研究
- Author:
Heng WANG
;
Lihuan LI
;
Yuntai YAO
;
Chenghui ZHOU
;
Nengxin FANG
;
Dong CHEN
- Publication Type:Journal Article
- Keywords:
Hypothyroidism;
Coronary artery bypass grafting;
Complication
- From:
Chinese Circulation Journal
2016;31(9):870-873
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study subclinical hypothyroidism (SCH) with its treatment in patients after coronary artery bypass grafting (CABG). Methods: A total of 1500 patients received CABG by the same surgical team in our hospital from 2010-06 to 2014-03 were retrospectively studied. According to thyroid function, the patients were divided into 2 groups: SCH group,n=107 and Normal group, n=1393. With 1:4 propensity score matching, there were 104 patients in SCH group and 416 patients in Normal group enrolled in our research. The rates of intra-aortic balloom pumping (IABP) implantation and peri-operational blood transfusion, mechanical ventilation time, new onsets of stroke, myocardial infarction and atrial ifbrillation, malignant arrhythmia, acute kidney injury and in-hospital mortality were observed. The outcome of treatment was assessed by single- and multi-factor analysis. Results: Compared with Normal group, SCH group showed increased mechanical ventilation time (23.3±47.9) h vs (15.0±5.5) h, P<0.05; more patients had mechanical ventilation time>12 h (89.4% vs 78.8%),P<0.05 and more patients had IABP implantation (3.8% vs 0.72%),P<0.05. SCH was related to mechanical ventilation time>12 h (OR=2.363, 95% CI 1.183-4.516) and IABP implantation (OR=6.126, 95% CI 1.190-31.537). The in-hospital death and other events were similar between 2 groups,P>0.05. Conclusion: Our research indicated that SCH was related to mechanical ventilation time and IABP implantation in patients after CABG.
