Relationship between cerebral artery stenosis and obstructive sleep apnea
10.3760/cma.j.issn.1671-7368.2016.10.009
- VernacularTitle:脑动脉狭窄与阻塞性睡眠呼吸暂停的关系研究
- Author:
Dongping ZHANG
;
Huihong WANG
- Publication Type:Journal Article
- Keywords:
Sleep apnea,obstructive;
Cerebral arterial stenosis
- From:
Chinese Journal of General Practitioners
2016;15(10):775-778
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of obstructive sleep apnea and atherosclerotic cerebral artery stenosis.Methods One hundred and twenty patients with acute cerebral infarction were enrolled in the study.Patients underwent polysomnography monitoring;according to the results, the sleep apnea/hypopnea index ( AHI) was ≥5/h in 60 patients ( OSA group) and AHI was <5/h in another 60 patients ( non-OSA group) .The degree, quantity and distribution of cerebral artery stenosis were compared between OSA and non-OSA group.Results The results showed that there were no significant differences in gender, age, NIHSS score and rates of diabetes, coronary heart disease, hyperlipidemia and smoking between two groups (P>0.05).The rates of increased BMI [(26.07 ±2.39)vs.(23.59 ±2.73) kg/m2] and hypertension [70%(42/60)vs.43%(26/60)] in OSA group were higher than those in non-OSA group (t=5.304,χ2 =7.603, all P<0.05).There were 47 (78.3%) patients in OSA group and 27 (45.0%) in non-OSA group presenting cerebral artery stenosis (χ2 =16.535, P<0.05), and both OSA group and non-OSA group displayed high proportion of intracranial artery stenosis ( 68.0% vs.81.5%, P>0.05 ) . The severity of cerebral artery stenosis in OSA group was higher than that in non-OSA group (χ2 =17.801, P<0.05).There were no significant differences in location distribution of stenosed cerebral arteries between two groups (P>0.05).Conclusion The study indicates that there is a close relationship between OSA and stenosis of atherosclerotic cerebral arteries.
