Mesenchymal stem cells in the treatment of bronchopulmonary dysplasia

VernacularTitle:间充质干细胞治疗支气管肺发育不良的研究进展
Author: Rong HUANG ; Li TAO ; Hui LYU
Publication Type:Journal Article
Keywords: Mesenchymal stem cell; Bronchopulmonary dysplasia; Anti-inflammatory; Regenerative re-pair; Paracrine
From: International Journal of Pediatrics 2016;43(9):677-680
CountryChina
Language:Chinese
Abstract: Bronchopulmonary dysplasia( BPD) is a chronic lung disease that commonly occurs in pre-term. Since the 1980s,with the advances in perinatal care,survival rate of preterm has been raised,while BPD continues to be a significant cause of morbidity and mortality for premature infants. However,the treatment effect of BPD is unsatisfactory. It is urgent to search for innovative ways to reduce the respiratory injury that caused by BPD as well as to improve the quality of life. In recent years,mesenchymal stem cells′( MSC) research has pro-vided a new way for the treatment of BPD. This review primarily summarizes the current status of the MSC ther-apies and its possible mechanism on BPD.