Protective effect of leuprorelin particle application before laparoscopic cystectomy on ovarian reserve function in ovarian endometriosis
10.3969/j.issn.1005-1678.2016.08.012
- VernacularTitle:腹腔镜下卵巢子宫内膜异位症囊肿剥除术前应用亮丙瑞林微球对卵巢储备功能的保护效果
- Author:
Yang YANG
;
Feixiang HUANG
- Publication Type:Journal Article
- Keywords:
leuprorelin;
laparoscopic;
endometriosis;
ovarian;
effect
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(8):55-57
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the protective effect of leuprorelin particle on ovarian reserve function applied before the laparoscopic cystectomy of ovarian endometriosis.Methods 106 patients with endometriosis treated from January 2015 to December 2015 in our hospital were selected.The subjects were divided into two groups according to the random number table, 53 cases of each group.The control group adopted the laparoscopic surgery;the observation group took the leuprorelin particle before the laparoscopic surgery.The operation condition, ovarian hormone and function were observed. Results The operation time and bleeding amount in observation group was better than control group ( P <0.05 ) .After surgery, the exhaust time between two groups had no significantly different.After surgery, the level of follicle stimulating hormone (FSH) in observation group was lower than control group; the level of estradiol (E2) in observation group was higher than control group (P <0.05); the level of luteinizing hormone (LH) between two groups had no significantly different.After surgery, the ovarian volume and antral follicle count ( AFC) in observation group was better than control group (P<0.05).Conclusion Before the laparoscopic cystectomy of ovarian endometriosis, the leuprorelin particle protects the ovarian function and morphology and has less impact in the level of hormone.
