Quality Study on Cinnabar-analysis of Dyeing Status for Cinnabar
10.6039/j.issn.1001-0408.2016.27.40
- VernacularTitle:朱砂染色现状分析
- Author:
Xiao XING
;
Zhimin LIU
;
Tongtong XU
;
Da GU
;
Yubing LIANG
;
Xin ZHANG
;
Jianlong YANG
- Publication Type:Journal Article
- Keywords:
Cinnabar;
Dyeing;
HgS;
Quality
- From:
China Pharmacy
2016;27(27):3864-3866
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the dyeing status of cinnabar and its pieces,and provide reference for its quality clinical safetey appicaton. METHODS:TLC was used for the qualitative identification of amaranth,carmine,erythrosine,acid red 73, 808 udan and indirubin. HPLC-MS was used to detect the 808 udan :HPLC conditions were as follows,column was Acquity UPLC BEH C18 with mobile phase of cetonitrile-0.1% formic acid(70∶30,V/V)at a flow rate of 0.3 ml/min,the detection wave-length was 520 nm;MS conditions were as follows,ion source was electrospray ionization source,scanning mode was positive ion scanning with full scanning tandem mass spectrometry,nebulizer pressure was 30 psi,drying gas was nitrogen,ion spray voltage was 4 000 V,collision energy was 30 V,and the injection volume was 5 μl. The volumetric method was used for content determi-nation of HgS. RESULTS:TLC spots of amaranth,carmine,erythrosine,acid red 73,808 udan and indirubin were clear and well-separated. 4 batches of 808 udan dyeing were included in the 18 batches of samples,6 batches had non-compliance contents (including 3 batches of 808 udan dyeing). CONCLUSIONS:Dyeing-doped and other quality problems exist in the cinnabaris in markets,which should be noticed.
