Research progress of microRNA-29 in tumors
10.3969/j.issn.1000-8179.2016.17.362
- VernacularTitle:miR-29在肿瘤中的研究进展
- Author:
Xuewei REN
;
Jicai ZHANG
- Publication Type:Journal Article
- Keywords:
microRNAs (miRNAs);
miR-29;
cancer
- From:
Chinese Journal of Clinical Oncology
2016;43(17):775-779
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA (miRNA) is an important gene regulatory molecule involved in the occurrence of a variety of diseases and is relat-ed to tumors. MicroRNA has become a new direction of oncology research in recent years. Studies showed that miR-29 plays dual roles, as tumor suppressor and tumor promoter. The expression of miR-29 significantly differs between cancer and normal tissues. miR-29 is predicted to be a biomarker for early diagnosis and prognosis prediction of certain cancer. This paper reviews the role of miR-29 in the pathogenesis of cancer.
