The application of mRNA in body lfuid identiifcation and tissue resource(
10.13618/j.issn.1001-5728.2016.05.009
- VernacularTitle:mRNA在体液斑迹鉴定与组织来源推断中的应用
- Author:
Hemiao ZHAO
;
Chong WANG
;
Wanshui LI
;
Zheng TU
;
Xiulan XU
;
Hui SUN
;
Lan HU
- Publication Type:Journal Article
- Keywords:
forensic biological evidence;
mRNA;
body lfuid stains;
tissue resource identiifcation
- From:
Chinese Journal of Forensic Medicine
2016;31(5):463-466
- CountryChina
- Language:Chinese
-
Abstract:
The identiifcation of body lfuid and their tissue resource is an important part of forensic medicine research. Conventional methods have imperfections like high false positive rate and may destroy biomaterial, which should be replaced by a new conifrmatory test. Highly-differentiated cells express speciifc mRNA molecules that can be used for body lfuid identiifcation. These mRNA markers can identify body lfuids like peripheral blood, menstrual blood, semen, saliva, vaginal secretion, skin-contact stains. This method have favorable sensitivity, speciifcity and can be detected after years, made it a ideal way to identify current body lfuids in the future. This review focus on the application of mRNA in body lfuid identiifcation and tissue resource.