Anomalous genotype observation of 4 multi-copy RM Y-STRs
10.13618/j.issn.1001-5728.2016.05.013
- VernacularTitle:4个多拷贝RMY-STR基因座的异常分型
- Author:
Wenqiong ZHANG
;
Chao XIAO
;
Jin YU
;
Yunshu JIA
;
Daixin HUANG
- Publication Type:Journal Article
- Keywords:
forensic biological evidence;
Y-STR;
rapidly mutating;
anomalous genotype
- From:
Chinese Journal of Forensic Medicine
2016;31(5):476-479
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe anomalous genotypes of 4 multi-copy RM Y-STRs in Han population in Hubei province. Methods 252 unrelated male samples were ampliifed using reported and newly designed primers, then detected and analyzed by AB 3130 genetic analyzer. Results A total of 25 anomalous multi-band patterns were observed in 20 samples corresponding to an incident rate of 7.94%. 5 anomalous genotypes were observed in DYF387S1 locus, 15 in DYF399S1, 1 in DYF403S1 and 4 in DYF404S1. Four samples showed extra alleles in more than one locus. Conclusion Anomalous genotype has high incident rates in RM Y-STR markers and requires extensive attention in forensic practice.
