Association between viral load and gestational diabetes mellitus in women with chronic hepatitis B
10.3969/j.issn.1006-5725.2016.19.001
- VernacularTitle:妊娠期慢性乙型肝炎病毒携带者病毒载量与妊娠期糖尿病的相关性
- Author:
Feifeng LI
;
Qitao HUANG
;
Chen HUANG
;
Yuanping ZHOU
;
Zhihua LIU
;
Weijuan ZENG
;
Haizhen WANG
;
Guosheng YUAN
;
Mei ZHONG
;
Yunfei GAO
- Publication Type:Journal Article
- Keywords:
Chronichepatitits B;
Pregnant women;
Viral load;
Gestational diabetes mellitus
- From:
The Journal of Practical Medicine
2016;32(19):3117-3119
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the GDM of 336 cases with chronic HBV in pregnancy. Methods According to HBV DNA≥1.0 × 103 IU/mL, participants were divided into HBV DNA (+) or (-) group. 409 cases without HBV were selected as control group. Differences on GMD incidence between groups and virus load and OGTT blood sugar correlation were compared. Results The incidence of GDM of HBV DNA (+) or (-) group was 16.77% and 17.71%, which is higher than that in HBV group (10.27%). The difference is significant (P < 0.05). The correlation index between HBV DNA and fasting blood-glucose is r = 0.005, P = 0.610, the result of which is not statistically significant. But correlation index between HBV DNA and blood sugar at 1 h , 2 h are r = 0.082, 0.086; P = 0.000, 0.000, the result of which is statistically significant. Conclusion The oc-currence of GDM were higher in HBV DNA (+) or (-) group. The viral load is positively related with blood sugar of glucose tolerance at 1 h or 2 h.
