Extraction Process Optimization of Fufang Jinsha Lidan Granule by Orthogonal Experiments
- VernacularTitle:正交试验优选复方金沙利胆颗粒的提取工艺
- Author:
Ailing YI
;
Fusheng ZOU
;
Bo YI
;
Guang DU
;
Conghui ZHOU
;
Yingying WEI
;
Wei CHEN
- Publication Type:Journal Article
- Keywords:
Fufang Jinsha Lidan granule;
Orthogonal experiments;
Extraction process
- From:
China Pharmacist
2016;19(10):1963-1965
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the extraction technology of Fufang Jinsha Lidan granule. Methods:According to the properties of traditional Chinese medicines in the formula, orthogonal experiments were used to optimize the extraction process of Fufang Jinsha Li-dan granule. The volume of water, boiling time and boiling frequency were used as the three influencing factors with three different lev-els in the orthogonal experiments. Moreover, the content of paeoniflorin and the yield of extract were chosen as the evaluation indices. The orthogonal experiments were carried out according to the L9 (34 ) orthogonal table. Results:The optimal extraction process of Fu-fang Jinsha Lidan granule was as follows:boiled twice, and one hour per time with 12-fold amount of water ( soaked for 30 min with 14-fold amount of water for the first extraction process) . Conclusion:The extraction process has such properties as high extraction rate, stability, simple operation, high yield of extract and controllable quality, which is worthy of wide application.
