Comparison the outcome of donation after brain death and cardiac death for adult-to-adult single kidney transplantation
10.3969/j.issn.1006-5725.2016.18.019
- VernacularTitle:脑死亡与心死亡后器官捐献成人供受者单肾移植效果比较
- Author:
Huanwen HUANG
;
Ding LIU
;
Jianmin HU
;
Hua CHEN
;
Min LI
;
Liuyang LI
;
Ying GUO
;
Ming ZHAO
- Publication Type:Journal Article
- Keywords:
Donation after brain death;
Donation after cardiac death;
Kidney transplant;
Clinical effect
- From:
The Journal of Practical Medicine
2016;32(18):3011-3014
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the outcome of adult-to-adult single kidney transplantation from donation after drain death and cardiac death. Methods The outcome of adult-to-adult single kidney transplantation from October 2012 to September 2015 in kidney transplantation center of Zhujiang Hospital was retrospectively analyzed. 53 recipients received donation from donors after brain death (DBD group) and 28 from cardiac death (DCD group). The deadline of follow-up is May 2016. Results During the period of observation, the mean follow-up was (17.26±10.85) months and patient's survival rate was 100%. When compared graft survival rate with the two groups, survival rate is 93.7% in DBD group and 92% in DCD group (χ2= 0.184,P = 0.668). There was no statistically significant difference (P > 0.05), the overall incidence of DGF was 28.4%. General DGF incidence is 28.4%, and DGF incidence between groups is χ2= 4.402,P = 0.036. Infection rate within 1 year is χ2= 4.507,P = 0.034, and the difference is significant (P < 0.05). There were no statistically significant difference (P > 0.05) in AR, eGFR of 1 month, proteinuria of 1 month after, transplantation and surgical complications. Conclusions Adult-to-adult single kidney transplantation from donation after cardiac death (DCD) has a higher rate of incidence of DGF, and the postoperative infection rate within 1 year. Renal transplantation from donation after cardiac death could have a good outcome.
