The effect of sevoflurane and propofol on postoperative cognitive function after abdominal surgery for elderly patients with diabetes
10.3969/j.issn.1006-5725.2016.17.038
- VernacularTitle:七氟醚与异丙酚对腹部手术老年糖尿病患者早期术后认知功能的影响
- Author:
Qiaoling ZHOU
;
Hongzhen LIU
;
Meijuan LIAO
;
Chengxiang YANG
;
Hanbing WANG
;
Hua LIANG
;
Xiaohong LAI
;
Jian HE
- Publication Type:Journal Article
- Keywords:
Sevoflurane;
Propofol;
Postoperative cognitive function;
Diabetes mellitus
- From:
The Journal of Practical Medicine
2016;32(17):2911-2914
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of sevoflurane and propofol on postoperative cognitive function after abdominal surgery for elderly patients with diabetes. Methods Seventy diabetic patients (aged 60~75 yr, ASAⅠorⅡ) underwent abdominal surgery and are included in the research. Diabetic patients were randomly divided into two groups (n=35): sevoflurane group(group DS) and propofol group (group DP). MMSE score, the attachment test, words memory test and Stroop color word test were carried and the results were recorded before operation (T1), postoperative 24 h (T2), 48 h (T3) and 1 w (T4). Results Compared with T1, patients′ MMSE score reduced at T2 and T3. Time spent in attachment test is longer at T2 and T3. Mistaken incidences in Stroop color words test 1, 2 and 3 are higher and time longer at T2. Time spent on Stroop color words test 2 and 3 is longer in T3. Words memory test reveals decline at T2 and T3, whose difference is statistically significant (P < 0.05). Cognitive dysfunction incidence in the two groups shows no statistical significance (P > 0.05). Conclusion Sevoflurane and propofol can result in postoperative cognitive dysfunction for elderly patients with diabetes within 48 h after abdominal surgery, there were no difference between the effects of them.
