Clinical Study on Combination of Modification ofChaihu Jia Longgu Muli Decoction with Psychological Intervention in Treatment of Post Tumor Depression
10.3969/j.issn.1005-5304.2016.11.006
- VernacularTitle:柴胡加龙骨牡蛎汤加减方联合心理干预治疗肿瘤后抑郁临床研究
- Author:
Jinhui WANG
;
Jianhua WANG
;
Hongwei LIU
;
Li MA
;
Shuyuan CHEN
;
Junquan YANG
;
Jing PENG
;
Xiuhong HAN
;
Jing LIU
- Publication Type:Journal Article
- Keywords:
Chaihu Jia Longgu MuliDecoction;
depression;
tumor;
psychological intervention
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2016;23(11):22-24
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of the combination of modification ofChaihu Jia Longgu MuliDecoction with psychological intervention in the treatment of post tumor depression.MethodsTotally 122 cases of post tumor depression were divided into treatment group and control group by simple numeration table random method, with 61 cases in each group. The treatment group was given modification ofChaihu Jia Longgu Muli Decoction orally, at the same time psychological intervention was given. The control group was given escitalopram oxalate tablets for 6 weeks. HAMD scale scores of the two groups were observed before and after treatment to evaluate the clinical efficacy. Changes in life quality of two groups were scored with SF-36 scale. The adverse reactions were also observed.ResultsAfter treatment, the HAMD score of treatment group was lower than control group (P<0.05). The total effective rate was 88.52% (54/61) in the treatment group and 72.13% (44/61) in the control group, with statistical significance (P<0.05). The scores of life quality of treatment group were higher than control group (P<0.05), and the incidence of adverse reactions was lower than control group (P<0.05).Conclusion Combination of modification ofChaihu Jia Longgu MuliDecoction with psychological intervention in the treatment of post tumor depression can significantly improve the depressive state and life quality of the patients with post tumor depression, which is better than the control group, without significant adverse reactions.
