Effect of local mild hypothermia on regional cerebral blood flow in patients with cerebral infarction assessed by 99mTc-ECD SPECT imaging
10.3969/j.issn.1006-5725.2016.18.002
- VernacularTitle:脑梗死患者99mTc－ECD SPECT／CT感兴趣区成像局部脑血流的特征
- Author:
Zhangwei LUO
;
Tianzi LI
;
Xuebin LI
;
Junfang HUANG
;
Lanqing MENG
;
Qingfeng LI
;
Ye LIANG
;
Jindu LI
- Publication Type:Journal Article
- Keywords:
Infarction;
SPECT/CT;
Cerebral blood flow perfusion imaging;
Regional cerebral blood flow
- From:
The Journal of Practical Medicine
2016;32(18):2948-2951
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the frequency of lesions detection in patients with cerebral infarction (CI) with SPECT/CT. To investigate fluctuation of regional cerebral blood flow (rCBF) and its relationship with clinical symptoms. Methods Sixty-seven CI patients without cerebellar lesion were randomly selected. The rCBF in the regions of interest (ROI) was examined by SPECT/CT, which was collected from the frontal lobe, temporal lobe, parietal lobe, occipital lobe, thalamus, basal ganglia and cerebellum. The rCBF index was calculated. The association between fluctuation of rCBF index and clinical symptoms of patients was explored. Results There were 251 positive regions in all viewing regions , the total positive rate was 31.2%. The left side was 38.1%, while the right side was 24.4% (χ2=17.522,P < 0.01). In normal group, there were no statistical difference of average rCBF between two halves (P > 0.05). However, the average rCBF on the left parietal lobe was lower (P < 0.01). The average rCBF in the abnormal group was lower than that in ipsilateral normal group (P < 0.01). The average rCBF index in the abnormal group was higher (P < 0.01). In normal group , the average rCBF on the frontal lobe and parietal lobe was low , but the average rCBF on the thalamus and basal ganglia was high (P < 0.01). In abnormal group, there were no statistical difference in the average rCBF (P >0.05). rCBF≥0.7 is a clinical sign of abnormal ROI. Conclusion 30% of ROI of CI patients have lesions and the positive rate of the left side was higher. The biological rCBF values of all lobes were different. Therefore, rCBF index could be used to reflect whether the ROI is normal. rCBF≥0.7 could be used as a sign to quantitatively assess abnormal ROI in clinical practice.
