Clinical value of inflammatory factors in sepsis
10.3969/j.issn.1006-5725.2016.17.023
- VernacularTitle:可溶性髓样细胞触发性受体1、降钙素原、C-反应蛋白在脓毒症中的临床价值
- Author:
Yunshan LUO
;
Yilin LIU
;
Xiamei DENG
;
Jian ZHANG
;
Li LI
- Publication Type:Journal Article
- Keywords:
Sepsis;
Soluble myeloid cell triggering receptor-1;
Procalcitonin;
C-reactive protein
- From:
The Journal of Practical Medicine
2016;32(17):2861-2863
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical value of sTREM-1, PCT, CRP in sepsis. Methods A prospective study was conducted and clinical data of related patients from January to October 2015 were collected. Thirty-nine cases of sepsis patients , 15 patients with SIRS and 12 normal controls were detected by ELISA then the prognostic value of sTREM-1, PCT, CRP was determined in sepsis. Results In sepsis and SIRS group, sTREM-1 and PCT level were significantly higher than those in control group (P < 0.05); CRP only in sepsis group and control group was statistically significant (P < 0.05). In sepsis group, sTREM-1,PCT and CRP were significantly higher than those in SIRS group (P < 0.05). The ROC curve analysis indicated that sTREM-1,PCT and CRP for SIRS and non SIRS area under the curve was 0.914,0.887 and 0.831 respectively. Conclusion sTREM-1 is a good indicator for early diagnosis of sepsis, and it has high sensitivity and specificity.
