Distribution and antimicrobial resistance of pathogens causing wound in-fection in army officers and soldiers in a military hospital
10.3969/j.issn.1671-9638.2016.10.002
- VernacularTitle:某部队医院官兵创伤感染的病原菌分布及耐药性
- Author:
Zhongyu XU
;
Jianlian GUO
;
Binlong XIAO
;
Huina LIU
;
Xianhai JIANG
- Publication Type:Journal Article
- Keywords:
trauma;
infection;
pathogen;
drug resistance;
drug resistance,microbial;
rational antimicrobial use
- From:
Chinese Journal of Infection Control
2016;15(10):726-729
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the distribution and antimicrobial resistance of pathogens causing wound in-fection in army officers and soldiers following military training injury,and provide reference for antimicrobial use in clinical anti-infection treatment.Methods Wound secretion from injured army patients who were admitted to a mili-tary hospital between January 2014 and June 2015 was performed bacterial culture and antimicrobial susceptibility testing.Results 647 pathogenic bacteria strains were isolated from 1 029 wound secretion specimens ,isolation rate was 62.88%,the top 6 isolated bacteria were Staphylococcus aureus (S .aureus ,29.99%,n =194),Escherichia coli (E.coli,19.32%,n=125),Pseudomonas aeruginosa (19.17%,n=124),Enterococcus spp .(13.60%,n=88), Klebsiella pneumoniae (K .pneumoniae ,7.73%,n =50),and Acinetobacter baumannii (A.baumannii,5.87%, n=38).S .aureus and Enterococcus spp .had high susceptibility to vancomycin,linezolid ,and daptomycin (resist-ance rates ≤3.41 %),44.33% of S .aureus were methicillin-resistant,2.27% of Enterococcus spp .were vancomy-cin-resistant .E.coli and K .pneumoniae had high susceptibility rates to piperacillin/ tazobactam (resistance rates were 1 .60% and 0 respectively),except A.baumannii,resistance rates of gram-negative bacteria to carbapenems were all low (resistance rates ≤4.00%).Conclusion Military clinicians should select appropriate antimicrobial agents according to antimicrobial susceptibility testing results,reduce the disability rate due to infection in trauma patients,and provide clinical support for the treatment of the wounded.
