The research progress of type 2 diabetes osteoporosis
10.3969/j.issn.1001-1978.2016.10.001
- VernacularTitle:2型糖尿病骨质疏松研究进展
- Author:
Guojing LIU
;
Xiaolei HU
;
Fazhong HE
;
Wei ZHANG
- Publication Type:Journal Article
- Keywords:
2 diabetes;
osteoporosis;
high glucose;
insulin;
drugs;
Inflammatory cytokine
- From:
Chinese Pharmacological Bulletin
2016;32(10):1333-1336
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes is a kind of metabolic syndrome, always hap-pening in the case of insufficient secretion of insulin or insulin resistance, inducing the increase of blood glucose. While, dia-betic osteoporosis is a kind of chronic diabetic complications, which happens when insulin secretion is absolutely or relatively insufficient and then the insufficiency induces imbalance of hor-mone, calcium phosphorus metabolic disorders, thus leading to the decline of bone mineral density and change of bone micro-structure. The overnutrition, less exercise and the environment change lead to the increased incidence of diabetes. For all the diabetes, type 2 diabetes accounts for about 90%. Patients with type 2 diabetes show the increasing risk of fracture. This review summarizes the recent advances in the influence of type 2 diabe-tes on bones.
