The value of IVIM imaging and DSC perfusion imaging in cerebral astrocytoma grading
10.3969/j.issn.1002-1671.2016.10.004
- VernacularTitle:IVIM与DSC灌注成像在脑星形细胞瘤分级中的诊断价值
- Author:
Lina ZHU
;
Hui ZHANG
;
Yan TAN
;
Xiaochun WANG
;
Jiangbo QIN
- Publication Type:Journal Article
- Keywords:
intravoxel incoherent motion;
dynamic susceptibility contrast-enhanced perfusion imaging;
cerebral astrocytoma
- From:
Journal of Practical Radiology
2016;32(10):1502-1505
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of MR intravoxel incoherent motion (IVIM)imaging and dynamic susceptibility contrast-enhanced(DSC)perfusion imaging in astrocytoma grading.Methods 22 patients with high grade astrocytoma and 28 patients with low grade astrocytoma underwent conventional MRI and IVIM,DSC scanning before operation.Parameters of IVIM included standard diffusion coefficient(ADCstandard ),slow diffusion coefficient(D),fast diffusion coefficient(D? ),fractional perfusion-related volume (f)values,and parameters of DSC included relative blood volume(rCBV),relative blood flow(rCBF)values of tumor solid part were measured quantitatively.The values between the two groups were compared by two samples t-test.By using ROC curve to evaluate the diagnostic efficacy of using IVIM and DSC alone or jointly.Results The ADCstandard ,D,rCBV,rCBF values of tumor solid part had significant differences between the groups(P<0.01).The D? and f values were no significant differences (P=0.130,P=0.379).The area under the ROC curve of the values showed that ADCstandard (0.823),D(0.854),rCBV(0.858),rCBF(0.871),D+rCBV(0.952),D+rCBF(0.953).Conclusion The D,rCBV,rCBF values are helpful to determine the grade of astrocytomas.The use of IVIM in combination with DSC may improve the diagnostic accuracy of astrocytoma grading.
