Evaluation of radiofrequency ablation in treatment of primary liver cancer and its risk factors

VernacularTitle:射频消融对原发性肝癌治疗评价及预后危险因素分析
Author: Bing CHEN ; Wei WU
Publication Type:Journal Article
Keywords: hepatocellular carcinoma; radiofrequency ablation
From: Journal of Practical Radiology 2016;32(10):1545-1548
CountryChina
Language:Chinese
Abstract: Objective To evaluate the radiofrequency ablation in treatment of primary and recurrent liver cancer and to explore the risk factors affecting prognosis.Methods 1 64 patients with primary and recurrent liver cancer underwent radiofrequency ablation treatment.The clinical data including liver function before and after treatment,alpha-fetoprotein (AFP),the rate of relapse and survivalwere retrospectively analyzed.The univariate Logistic regression analysis was used to analyzed the risk factors associated with the prognosis.Then the risk prognostic factors were analyzed using COX risk model.Results After treatment,AFP and liver function were significantly improved in patients (P<0.05);Complete tumor ablation rate was 87.50%.After cancer treatment 1,2,3,4 years,the recurrence rate was 17.9%,29.9%, 45.9% and 55.0% respectively.Conclusion Radiofrequency ablation is an effective treatment for primary liver cancer treatment,the risk factors affecting prognosis include tumor differentiation,tumor recurrence,TNM stage,AFP,intraoperative blood transfusion, surgical,cancer and surgical site before surgery transaminase levels.