Relationships between the spine muscle degenerative changes and the aging in elderly males by quantitative computed tomograph
10.3969/j.issn.1671-8348.2016.30.006
- VernacularTitle:定量CT 研究中老年男性椎后肌群退行性改变与年龄的相关性
- Author:
Ling WANG
;
Chen WANG
;
Xue HOU
;
Xiaoguang CHENG
- Publication Type:Journal Article
- Keywords:
vertebral muscle;
degeneration;
muscle fat infiltration;
quantitative CT
- From:
Chongqing Medicine
2016;45(30):4193-4196
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the age related decline in spine muscle volume and fat content in healthy elderly males . Methods Totally 88 males aged 50-79 years were selected from the patients who underwent quantitative CT (QCT) exam of lum‐bar spine .They were subgrouped by 50- <60 years ,60- <70 years and 70-79 years .The muscle fat area ,skeletal muscular area , muscle fat infiltration (MFI) ,abdominal visceral fat volume and subcutaneous fat volume ,abdominal total fat volume were measured by the QCT software .Statistical analysis was performed using intraclass correlation coefficient ,ANOVA with post hoc Bonferroni correction ,Pearson correlation analysis and multiple regression analysis .Results Compared to other two groups ,subjects in 70-79 years subgroup had highest muscle fat area/MFI and least skeletal muscular mass(P<0 .05) .Age‐dependent correlation was found in muscle fat mass(r=0 .381 ,P<0 .05) and MFI(r=0 .358 ,P=0 .001) ,but no obvious correlation was found between age and skeletal muscular mass .Age was the only factor entered into the all three paravertebral muscle composition regression equations , meaning age may had an important influence on paravertebral muscle degeneration .Conclusion Lumbar paravertebral muscle de‐generation in elderly men is correlated with the aging and MFI ,which may play a important role in the normative age‐related decline of skeletal muscle .
