Comparison of clinical pathological characteristics in ovarian preserving patients with stageⅠB1 cervical adenocarcinoma and squamous cell carcinoma
10.3969/j.issn.1671-167X.2016.05.006
- VernacularTitle:ⅠB1期宫颈腺癌和鳞癌患者保留卵巢的临床病理特征比较
- Author:
Jun HU
;
Peizi ZHENG
;
Lirong ZHU
- Publication Type:Journal Article
- Keywords:
Uterine cervical neoplasms;
Adenocarcinoma;
Carcinoma,squamous cell;
Ovariectomy;
Survival analysis
- From:
Journal of Peking University(Health Sciences)
2016;48(5):783-787
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the risk and prognostic of patients with stage ⅠB1 cervical adenocar-cinoma.Methods:The clinical data of 139 patients with stage ⅠB1 cervical adenocarcinoma treated at Department of Gynecology and Obstetrics in Peking University First Hospital from August 1994 to April 2015 were retrospectively reviewed,which included 38 cases of cervical adenocarcinoma and 101 cases of cervical squamous cell carcinoma.A comparison was made between ovarian preserving group and bilateral oophorectomy group,in order to justify the risk and prognosis of ovarian preserving patients.Results:The 5-year cumulative survival rate of stage ⅠB1 cervical adenocarcinoma and squamous cell carcinoma were 89.1% and 92.9% respectively with significant difference (P =0.034).One ovarian metastasis case was observed among the 32 cervical adenocarcinoma patients of bilateral oophorectomy,while another ovarian metastasis case was observed among 54 cervical squamous cell carcinoma patients of bila-teral oophorectomy.The ovarian metastasis rate was 3.1% (1 /32)and 1.8 % (1 /54)respectively with no statistical difference (P =0.574).The cumulative 5-year survival of 6 ovarian preserving patients with cervical adenocarcinoma was 80.1%,while that of 47 ovarian preserving patients with cervical squa-mous cell carcinoma was 94.6% (P =0.127).There was no statistical difference between the survival curve of the two groups.Conclusion:The prognosis of stageⅠB1 cervical adenocarcinomas was somewhat poorer than that of cervical squamous cell carcinoma.However it was still reasonable to perform ovarian preservation among young patients of stageⅠB1 cervical adenocarcinoma with no high risk factors.
