Drug Resistance and Homology Analysis of Multi-drug Resistant Acinetobacter Baumannii in Orthopaedic Hospital

VernacularTitle:骨科医院多重耐药鲍曼不动杆菌耐药性与基因同源性分析
Author: Heping ZHAO ; Jihan WANG ; Wenyan JIANG ; Bei ZHANG ; Jing ZHAO ; Yan YU
Publication Type:Journal Article
Keywords: MDR-AB; drug resistance; REP-PCR; homology
From: Journal of Modern Laboratory Medicine 2016;31(5):88-90
CountryChina
Language:Chinese
Abstract: Objective To investigate the drug resistance and homology status of Multi-drug Resistant AcinetobacterBauman-nii (MDR-AB)in orthopaedic hospital.Methods 34 strains MDR-AB were isolated from 2016.1~2016.7 for DNA extrac-tion and were typed by repetitive extragenic palindromie-polyrnerase chain reaction (REP-PCR).Results The resistance rate of MDR-AB were ≥70% to 15 of 17 antimicrobials,except to cotrimoxazole (14%)and levofloxacin (61%),34 strains of MDR-AB were divided into three types by REP-PCR including typeⅠ,typeⅡ and typeⅢ.Conclusion Drug resistance of MDR-AB was severe and mainly composed of the same genotype (typeⅠ).Rational use of antimicrobial and regular mo-nitoring of drug resistance is necessary to reduce the nosocomial transmission.