Comparison of clinical manifestations and electrophysiological features in patients with chronic inflamma-tory demyelinating polyneuropathy and Type-I Charcot Marie Tooth Disease
10.3969/j.issn.1002-0152.2016.08.010
- VernacularTitle:慢性炎性脱髓鞘性多发性神经病与腓骨肌萎缩症-I型的临床及神经电生理比较
- Author:
Jingjie LIU
;
Ping HAN
;
Zhen GAO
;
Fuhua GONG
;
Xiaolin MA
;
Li XIANG
- Publication Type:Journal Article
- Keywords:
Chronic inflammatory demyelinating polyneuropathy;
Type-I Charcot-Marie-Tooth;
Disease(CMT-I) Electrophysiology
- From:
Chinese Journal of Nervous and Mental Diseases
2016;42(8):493-497
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To compare clinical manifestations and electrophysiological features in patients with chron?ic inflammatory demyelinating polyneuropathy (CIDP) and Type-I Charcot Marie Tooth Disease (CMT-I) for guiding dif?ferential diagnosis. Methods Data including clinical manifestations and electrophysiological indexes was collected from thirty-one CIDP cases and 28 CMT-I cases. Correlation analysis was used to assess the association of the severity of electrophysiology with the severity of clinical symptoms. Results There were statistically significant differences in onset site, sensory dysfunction, foot deformity and cerebrospinal fluid protein between these two groups (P<0.05). There were significant differences in indexes of nerve conduction and needle electromyography between these two groups (P<0.05). The severity of clinical symptoms was not related with the severity of electrophysiology in CMT-I group (r=0.27,P>0.05). Conclusions Differential diagnoses of CIDP and CMT-I can be made based on clinical manifestations and electro?physiological features.
