Trueness Controls of Clinical Laboratory to Assess Bias
10.3969/j.issn.1671-7414.2016.05.044
- VernacularTitle:临床检验正确度控制品-评估偏倚
- Author:
Xiaoyan ZHANG
;
Wei WANG
;
Zhiguo WANG
- Publication Type:Journal Article
- Keywords:
trueness controls;
bias;
statistical quality control;
systematic error
- From:
Journal of Modern Laboratory Medicine
2016;31(5):147-149
- CountryChina
- Language:Chinese
-
Abstract:
Precision controls monitor assay random error (reproducibility),accuracy controls assess total error,both random error and systematic error,and trueness (bias)of an assay represents systematic error.A trueness control should be metro-logical traceable,ideally with a target value determined by use of a reference material or a reference method,without metro-logical traceable to a reference measurement system,patient test results for the same patient from different laboratories may not be comparable.A trueness control should be commutable and its analytical response to a reference method and a routine field method should be equivalent to that of a patient sample.And trueness control values should generally be set at medical decision levels and be prepared by the providers of reference materials and manufactured in the same fashion as a calibrator.
