A Case of Chronic Granulomatous Disease in which Enterococci were Observed in Culture.
- Author:
Kyung Lae CHO
;
Jeong Hee KIM
;
Eun Jeong KIM
;
Chur Woo YOO
;
Chun Soo KIM
;
Un Seok NHO
;
Chul Kyu KIM
- Publication Type:Case Report
- Keywords:
Chronic granulomatous disease;
Catalase negative Enterococcus
- MeSH:
Abscess;
Autopsy;
Bacteria;
Catalase;
Eczema;
Enterococcus;
Fever;
Fungi;
Granulomatous Disease, Chronic*;
Korea;
Liver Abscess;
Lung;
Lymphatic Diseases;
Phagocytes;
Pyoderma;
Skin;
Superoxides
- From:Journal of the Korean Pediatric Society
2000;43(6):846-850
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Chronic granulomatous disease(CGD) is a genetically inherited disorder caused by the failure of phagocytic cells to produce superoxide. It is characterized by frequent and uncontrollable infection which often lead to death in early childhood. The first clinical signs may be confined to skin and manifest themselves as abscesses, pyoderma, eczema or draining sinuses. The disease was first reported in 1957 and thereafter the biomolecular mechanism has been found. The first report in Korea was an autopsy case in 1979 and since then there have been a few case reports. This disease is diagnosed by symptoms, such as high fever, cervical lymphadenopathy, skin nodule, lung field infiltration, periumbilical abscess, liver abscess, pyoderma and pericordal abscess. The pathogen here were catalase producing bacteria and fungi. However, we have experienced a case of CGD, in which symptoms were perianal, scrotal abscesses and lung field nodular infiltration. In this case the pathogen was found as a catalase negative Enterococcus. (J Korean Pediatr Soc 2000;43-846-850)
