The influence of smoking on olfactory disorder in patients with Parkinson's disease
- VernacularTitle:吸烟对帕金森病患者嗅觉障碍的影响
- Author:
Yongqing CHENG
;
Zhitao SHA
;
Youyong TIAN
- Publication Type:Journal Article
- Keywords:
Parkinson disease;
olfactory disorder;
smoking
- From:
Journal of Clinical Neurology
2016;29(5):370-373
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of smoking on olfactory disorder in Parkinson's disease (PD). Methods According to smoking or not, 167 PD patients ( PD group) and 100 normal controls ( normal control group) were divided into smoking subgroups and non-smoking subgroups.The olfactory identification threshold was tested by T&T olfactory assessment.Results Compared with normal control group, the scores of MMSE and montreal cognitive assessment in PD group were significantly decreased ( all P<0.05 ) , age, smoking history, the rate of male had no statistical significance ( all P>0.05 ) .The olfactory identification threshold in PD group was significantly higher than normal control group (t=6.785, P=0.000).Compared with PD smoking subgroup, the olfactory identification threshold in non-smoking subgroup was significantly higher (t=-3.000, P=0.003).The olfactory identification threshold in normal control smoking subgroup was significantly lower (t=0.784, P=0.435). The olfactory identification threshold of PD smokers had no correlation with smoking pack-years or duration ( r=-0.104, P=0.441;r=-0.156, P=0.246) .Conclusion Smoking may protect olfactory disorder in PD patients, and it has no correlation with smoking pack-years or duration.
