Thromboelastographic Dynamic Monitoring and Clinical Application in Patients Experiencing Acute Ischemic Stroke and Receiving Reteplase
10.3969/j.issn.1671-7414.2016.05.040
- VernacularTitle:血栓弹力图动态监测AIS患者瑞通立静脉溶栓过程及其应用
- Author:
Hongxia XU
;
Laichun SONG
- Publication Type:Journal Article
- Keywords:
acute ischemic stroke;
thromboelastography;
reteplase
- From:
Journal of Modern Laboratory Medicine
2016;31(5):137-139
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of reteplase on the thromboelastogram tracing of patients experiencing acute is-chemic stroke(AIS).Methods Selected 43 AIS inpatients in the Third People’s Hospital of Liaocheng from October,2013 to August,2015,who received reteplase less than 4.5 hours after the onset of syndrome of AIS.Blood samples were obtained before reteplase administration and at 0.5,1,2 and 4 hours after reteplase administration and measured by thromboelastogra-phy.Results The parameters R,K,Angle and MA of the thromboelastogram had changed after beginning administration of reteplase.The R value at 0.5 h after thrombolysis was significantly higher than that before thrombliysis,however,the R Value at 1h after thrombolysis was the most highest,and the K value.At 0.5 h after thrombolysis was the highest.At 0.5 h after thrombolysis MA and Angle values were the lowest,the differences were statistically significant (P<0.001).Conclu-sion The study suggests that the thromboelastogram is an useful tool for determining changes in the coagulation system of patients receiving reteplase.
