Identification of human neutrophil antibodies among volunteer blood donors in one district
10.3969/j.issn.1673-4130.2016.20.008
- VernacularTitle:某地区无偿献血者中性粒细胞特异性抗体筛查分析
- Author:
Hecai YANG
- Publication Type:Journal Article
- Keywords:
HNA;
immune-mediated transfusion related adverse reaction;
transfusion safety
- From:
International Journal of Laboratory Medicine
2016;37(20):2823-2824
- CountryChina
- Language:Chinese
-
Abstract:
Objective To elucidate the distribution of human neutrophil (HNA ) antibodies among volunteer blood donors in Henan and estimate the risk rate of immune‐mediated transfusion related adverse reaction caused by HNA antibodies .Methods 156 females and 80 males were collected randomly from volunteer blood donors in Henan .All the samples′HNA antibodies were detec‐ted using LABScreen Multi kit .Results The data showed that among the 236 volunteer blood donors ,the positive rate of HNA an‐tibodies was 5 .77% (9/156)in females ,while the rates were 5 .00% (4/80)for males .Among the positive donors ,there were 7 anti‐HNA 1A ,4 anti‐HNA 4A ,1 anti‐HNA 1A/HNA 4A and anti‐HNA 1A/HNA 1C .Conclusion The frequency of HNA antibodies in females is same as the males .Our study is to elucidate the distribution of human neutrophil antibodies among volunteer blood do‐nors in Henan and estimate the risk rate of immune‐mediated transfusion related adverse reaction caused by HNA antibodies ,there‐fore it could provide theoretical basis for clinical transfusion safety .
