Application of multi-tumor marker protein chip for tumor screening
10.3969/j.issn.1673-4130.2016.20.012
- VernacularTitle:肿瘤标志物蛋白芯片用于肿瘤筛查的实用性研究
- Author:
Jinlong DU
;
Weihua WU
;
Qiang WU
- Publication Type:Journal Article
- Keywords:
tumor marker;
protein chip;
screening
- From:
International Journal of Laboratory Medicine
2016;37(20):2833-2835
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the application of multi‐tumor marker protein chip for early tumor screening and diagnosis . Methods From Nov .2011 to Dec .2015 ,10 736 samples ,including people receiving physical examination and with high risk of canc‐er in Fengcheng Hospital were collected .Twelve tumor markers in serum(AFP ,CEA ,NSE ,CA125 ,CA153 ,CA242 ,CA199 ,PSA ,f‐PSA ,FER ,β‐HCG and HGH)were measured by multi‐tumor markers protein chip detective system ,and the results were analyzed . Results We found out 967 samples with positive markers in the 10 736 samples .Of which ,496 were male and 471 were female ,the positive rate were 4 .62% and 4 .39% respectively .Totally 473 were diagnosed with tumor confirming by clinical pathology ,postive diagnosis rate was 48 .91% .Conclusion The multi‐tumor marker protein chip (C12 system) can detect multiple tumor markers simultaneously to improve screening process and achieve rapid detection ,w hich has higher positive detectiong rate and clinical value on diagnosing malignant tumor in early stage .
