The role of FoxM1 in the development and treatment of breast cancer
10.11904/j.issn.1002-3070.2016.05.015
- VernacularTitle:叉头框蛋白 M1在乳腺癌的进展及治疗耐药中的作用
- Author:
Huiying LI
;
Jingshu GENG
- Publication Type:Journal Article
- Keywords:
FoxM1;
Transcription factor;
Breast cancer;
Therapy
- From:
Practical Oncology Journal
2016;30(5):458-462
- CountryChina
- Language:Chinese
-
Abstract:
FoxM1 is a specific transcription factor related to proliferation .Previous studies have found that FoxM1 can enhance the proliferation ,metastasis and invasion of cancer cells ,and play a crucial role in canc-er.Recent studies indicate that the abnormal expression of FoxM 1 plays an important role in breast cancer ,and its overexpression is negatively correlated with the overall survival of patients .For the early diagnosis of breast canc-er,clinical prognosis and study on combination therapy provides a new direction .This article reviews the relation-ship between FoxM1 and breast cancer .
