Dose optimization of continuous renal replacement therapy in sepsis-induced acute kidney injury

VernacularTitle:脓毒症合并急性肾损伤患者连续性肾脏替代治疗剂量的选择
Author: Jun CUI ; Junfeng ZHOU ; Xianyao WAN
Publication Type:Journal Article
Keywords: High volume hemofiltration; Standard volume hemofiltration; Sepsis
From: Chinese Critical Care Medicine 2016;28(10):957-960
CountryChina
Language:Chinese
Abstract: Sepsis is a life-threatening organ dysfunction caused by dys-regulated host response to infection. Acute kidney injury (AKI) caused by sepsis is one of the most common and severe clinical disease, which incidence and mortality remains high level, and has poor clinical outcomes. Continuous renal replacement therapy (CRRT) is an indispensable tool for the treatment of critically ill patients with severe AKI, but there is no consensus on the appropriate treatment dose of CRRT. By reviewing the process of high volume hemofiltration (HVHF) and standard volume hemofiltration (SVHF), comparing their benefits and risks, and making suggestions for therapeutic schedule improvement, reference for clinical work was provided.