Compatible Stability of Cefmenoxime for Injection with Ganciclovir for Injection
10.6039/j.issn.1001-0408.2015.29.12
- VernacularTitle:注射用盐酸头孢甲肟与更昔洛韦的配伍稳定性考察Δ
- Author:
Jianxin WANG
;
Zhiyun HUANG
;
Junli GUO
;
Jizhang YANG
- Publication Type:Journal Article
- Keywords:
Cefmenoxime;
Ganciclovir;
HPLC;
Compatibility;
Stability
- From:
China Pharmacy
2015;(29):4066-4068
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the compatible stability of Cefmenoxime for injection with Ganciclovir for injection in 0.9% Sodium chloride injection and 5% Glucose injection. METHODS:At room temperature,the appearance and pH of the mix-tures were observed after Cefmenoxime for injection was compatible with Ganciclovir for injection. HPLC method was adopted to determine the content of them. RESULTS:No significant change was noted for the mixture in appearance and pH value. The con-tent of ganciclovir was more than 98%,but that of cefmenoxime decreased to 75.33%. CONCLUSIONS:Cefmenoxime for injec-tion can not be mixed with Ganciclovir for injection in 0.9%Sodium chloride injection and 5%Glucose injection .
