Clinical Observation of Autoserum Eye Drops in the Treatment of Filamentosa Keratitis after Excimer Laser Corneal Refractive Surgery
10.6039/j.issn.1001-0408.2015.29.31
- VernacularTitle:自体血清滴眼液治疗准分子激光角膜屈光手术后丝状角膜炎的临床观察
- Author:
Li ZENG
- Publication Type:Journal Article
- Keywords:
Excimer laser corneal refractive surgery;
Filamentous keratitis;
Autoserum eye drops;
Therapeutic efficacy
- From:
China Pharmacy
2015;(29):4121-4123
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe clinical efficacy and safety of Autoserum eye drops in the treatment of filamentary kerati-tis after excimer laser corneal refractive surgery. METHODS:46 patients (90 eyes) with filamentary keratitis after excimer laser corneal refractive surgery were selected and randomly divided into control group and observation group with 23 cases(45 eyes)in each group. The control group was given clearing mesh+wearing soft contact lens+bFGF eye drops;the observation group was giv-en clearing mesh+ wearing soft contact lens + Autoserum eye drops. The clinical efficacy,cure time,recurrence rate and ADR were compared between 2 groups. RESULTS:The total effective rate of observation group was 93.3%,which was higher than that (82.2%)of the control group,with statistical significance(P<0.05);the cure time of observation group was(2.7±1.1)d,which was shortened significantly compared with control group [(3.5±1.2)d],with statistical significance(P<0.05). The recurrence rate of filamentous keratitis was 4.4% in observation group and 15.6% in control group;the observation group was significantly lower than the control group,with statistical significance(P<0.05). During the treatment,there were 1 case(1 eyes)of corneal epitheli-al edema in observation group and 2 cases (2 eyes) of corneal epithelial edema in control group,there was no statistical signifi-cance(P>0.05). CONCLUSIONS:In the treatment of filamentous keratitis after excimer laser corneal refractive surgery,therapy of clearing mesh+wearing soft contact lens+Autoserum eye drops have high total effective rate,low recurrence rate and short cure period with less ADR.
