Clinical Observation of Fuzheng Huaji Pills in the Adjunctive Treatment of Middle and Advanced Primary Liver Cancer
10.6039/j.issn.1001-0408.2015.26.34
- VernacularTitle:扶正化积丸辅助治疗中晚期原发性肝癌的临床观察
- Author:
Da WANG
;
Yan WANG
;
Shuquan CHEN
- Publication Type:Journal Article
- Keywords:
Fuzheng huaji pills;
Primary liver cancer;
Adjunctive efficacy;
Hemorheology
- From:
China Pharmacy
2015;(26):3706-3708
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical efficacy and ADR of Fuzheng huaji pills in the adjunctive treatment of mid-dle and advanced primary liver cancer. METHODS:122 patients with middle and advanced primary liver cancer who had lost the chance or were unwilling to accept surgery,radiotherapy or chemotherapy were randomly divided into control group (61 cases) and study group(61 cases). The control group received conservative treatment such as hepatoprotecives;the study group was treat-ed with Fuzheng huaji pills 1 pills per time,3 times a day,additionally for 30 days. The tumor volume changes,major clinical symptom scores,quality of life,hemorheology indexes and alpha-fetal protein(AFP),lab index and ADR were compared between 2 groups. RESULTS:After treatment,tumor stable rate of study group was 67.2%,the improvement rate of life quality 27.9%, and AFP(563.35±143.17)pg/L;the scores of liver pain,abdominal distension,loss of appetite and fatigue,and plasma viscosity, whole blood viscosity,erythrocyte sedimentation rate decreased greatly,there were significant differences,compared to control group (P<0.05). One patient in study group suffered from diarrhea,and the symptom was relieved after symptomatic treatment;no obvious ADR was found. CONCLUSIONS:Through stabling tumor, improving major clinical symptom, life quality and hemorheology indexes,Fuzheng huaji pills play a synergistic treatment effect on primary liver cancer.
