Cost-effectiveness Analysis of TCM Injection in Adjuvant Treatment of Coronary Heart Disease with Heart Failure
10.6039/j.issn.1001-0408.2015.26.03
- VernacularTitle:两种中药注射剂辅助治疗冠心病心衰的成本-效果分析
- Author:
Wenlin WANG
;
Min WU
;
Yanhua ZHAO
;
Shimao NI
- Publication Type:Journal Article
- Keywords:
Coronary heart disease;
Heart failure;
Shenmai injection;
Salvianolate for injection;
Cost-effectiveness analysis
- From:
China Pharmacy
2015;(26):3614-3616
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the cost and effectiveness of Shenmai injection and Salvianolate for injection in adjuvant treatment of coronary heart disease with heart failure. METHODS:In prospective randomized controlled clinical study,103 pa-tients with coronary heart disease with heart failure were randomized into 2 groups:55 patients in group A received Shenmai injec-tion 50 ml added into 5% Glucose solution 250 ml intravenously on the basis of routine treatment,once a day;48 patients in group B received Salvianolate for injection 200 mg added into 5% Glucose solution 250 ml intravenously on the basis of routine treatment,once a day;treatment course lasted for 2 weeks. The improvement of clinical indicators and ADR were observed before and after treatment;2 drug treatment programs were evaluated and analyzed with pharmacoeconomics. RESULTS:Total effective rates of group A and B were 89.09% and 72.92%,with statistical significance(P<0.05);the incidence of ADR in group A and B were 9.09% and 12.50%,there was no statistical significance(P>0.05). The cost-effectiveness ratio of group A was significantly lower than that of group B,with statistical significance(P<0.05);the results of sensitivity analysis was consistent with it,indicat-ing the cost of Shenmai injection was in low level. CONCLUSIONS:Shenmai injection is more economic in adjuvant treatment of coronary heart disease with heart failure.
