Analysis of 158 Cases of ADR Caused by Chinese Patent Medicines in Our Hospital
10.6039/j.issn.1001-0408.2015.26.22
- VernacularTitle:我院中成药致不良反应158例分析
- Author:
Lin HE
;
Jin HE
;
Qiongyao ZENG
;
Yang PENG
;
Peihong YANG
;
Mo CHENG
- Publication Type:Journal Article
- Keywords:
Chinese patent medicines;
ADR;
Investigation and Analysis;
Rational drug use
- From:
China Pharmacy
2015;(26):3672-3674
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the characteristics and factors of ADR caused by Chinese patent medicine(CPM)and to provide reference for rational drug use and safety evaluation in the clinic. METHODS:158 cases of ADR caused by CPM collect-ed from our hospital during Jan.2009-Dec.2014 were analyzed. RESULTS:The occurrence of ADR caused by CPM was related to patient’s age,route of administration,category of drugs,irrational drug-use and so on. The incidence of ADR in patients over the age of 60 was the highest (31.01%),the largest number of ADR were caused by intravenous injection (79.11%),ADRs were most likely caused by blood-regulating preparation and dissipate blood stasis preparation (79.75%);ADR manifested as lesion of skin and its appendents(43.01%),followed by gastro-intestinal injury(16.06%)and whole-general injury(10.36%). The severe ADR was anaphylactoid reaction;after symptomatic treatment,the prognosis is good. CONCLUSIONS:According to syndrome differentiation and individual difference,CPM should be used rationally,and great importance should be attached to drug use moni-toring to reduce the incidence of ADR.