The clinical feature and microbiological etiology of patients with infective endocarditis
10.3760/cma.j.issn.0578-1426.2016.10.010
- VernacularTitle:感染性心内膜炎的临床特点及病原菌分析
- Author:
Keng LI
;
Fuen ZHANG
;
Aiping WANG
;
Guangfa ZHU
- Publication Type:Journal Article
- Keywords:
Endocarditis,bacterial;
Microbial sensitivity tests;
Pathogens
- From:
Chinese Journal of Internal Medicine
2016;55(10):774-778
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features,pathogenic distribution and drug susceptibility of patients with infective endocarditis (IE).Methods Clinical data of IE patients were collected,who were admitted to Capital Medical University Affiliated Beijing Anzhen Hospital from January 2012 to March 2015.Results Three hundred and three IE patients were enrolled with age of (43 ± 16)years old.Fever (85.5％)and cardiac murmur (62.4％)were the most common clinical presentations.Congenital heart diseases was the leading underlying diseases in IE patients.Non rheumatic valve diseases (13.5％) followed.Vegetations were found in 90.4％ (274/303) patients.Streptococcus which accounted for 44.2％ was the major pathogen of IE.Staphylococcus (28.9％) was the second common pathogen.Gramnegative bacteria were diversified in categories.Gram-positive cocci were consistently sensitive to vancomycin and linezolid.Conclusions Congenital heart disease is the main underlying disease related to IE.Streptococcus is still the primary pathogen.Gram-positive cocci keep good sensitivity to vancomycin and linezolid.
