The significance of peripheral blood natural killer cell surface CD107a, NKG2D and serum sMICA in patients with extranodal NK/T cell lymphoma, nasal type
10.3760/cma.j.issn.0578-1426.2016.11.012
- VernacularTitle:鼻型结外NK/T细胞淋巴瘤患者外周血NK细胞表面CD107a、NKG2D表达与血清sMICA水平及意义
- Author:
Jianxin LIU
;
Jingwen WANG
;
Xueying CUI
- Publication Type:Journal Article
- Keywords:
Lymphoma;
Killer cells,natural
- From:
Chinese Journal of Internal Medicine
2016;55(11):872-874
- CountryChina
- Language:Chinese
-
Abstract:
The expression of CD107a,NKG2D on the surface of natural killer (NK) cells and serum soluble major histocompatibility complex class Ⅰ chain-related A (sMICA) level in patients with extranodal NK/T cell lymphoma,nasal type (ENKL) were detected.We found that CD107a expression was reduced on the surface of NK cells,suggesting impaired NK cell activity in ENKL patients,which may result from decreased NKG2D expression.
