Alzheimer's disease and cataracts
10.3760/cma.j.issn.0254-9026.2016.08.028
- VernacularTitle:阿尔茨海默病与白内障
- Author:
Junhua WEN
;
Xiaosu YANG
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
Amyloid beta-protein;
Cataract
- From:
Chinese Journal of Geriatrics
2016;35(8):910-912
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease (AD) is an age-related progressive neurodegenerative disease.As the most common type of senile dementia disease,AD has no effective methods for early diagnoses.AD is characterized by the deposition of intracellular amyloid β (Aβ) plaques and extracellular neurofibrillary tangles (NFT) in the brain.In addition to allomnesia and cognitive disorder,ocular manifestation such as cataracts exists in AD patients.Studies have shown that amyloid-β (Aβ) is deposited not only in the brain but also in crystalline lens.For its structure and special location,crystalline len is more accessible for imaging than the brain,which can provide a simple,convenient and early diagnosis method for AD.Hence,it is worth investigating the relationship between Alzheimer's disease and cataracts.
