Clinical Observation of Pidotimod Combined with Triamcinolone Acetonide in the Treatment of Oral Lichen Planus
10.6039/j.issn.1001-0408.2015.27.10
- VernacularTitle:匹多莫德联合曲安奈德治疗口腔扁平苔藓的临床观察
- Author:
Ziyong LI
;
Xin YU
- Publication Type:Journal Article
- Keywords:
Pidotimod;
Triamcinolone acetonide;
Oral lichen planus;
Clinical efficacy;
Safety
- From:
China Pharmacy
2015;(27):3772-3773
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the efficacy and safety of pidotimod combined with triamcinolone acetonide in the treat-ment of oral lichen planus(OLP). METHODS:Data of 60 patients with OLP were retrospectively analyzed and divided into obser-vation group(35 cases)and control group(25 cases)by different medication. Control group was treated with triamcinolone aceton-ide 1 ml+2% Lidocaine injection 1 ml,embrocated in the local lesion area according to lesion size,3 times a day;observatioh group was additionally treated with Pidotimod dispersible tablets 800 mg between meals based on the treatment of control group, twice a day,and then changed to 800 mg,orally,once a day after 2 weeks. The treatment course was 4 weeks. The clinical effica-cy and incidence of adverse reactions in 2 groups were observed. RESULTS:After 1 and 3 month(s),the total effective rates in ob-servation group were significantly higher than control group,the difference was statistically significant(P<0.05). There was no sig-nificant difference in the incidence of adverse reactions between 2 groups(P>0.05). CONCLUSIONS:Pidotimod combined with triamcinolone acetonide has significant efficacy in the treatment of OLP,with good safety.
